Sleeping Tips - Strategies, Tips and Techniques You Can Use to Finally Put an End to Insomnia and Sleep Deprivation
Insomnia refers to a prolonged inability to get adequate sleep. About one out of three people have insomnia sometime in their life. Chronic sleep problems can seriously disrupt your life, taking a heavy toll in both your personal and professional relationships.
While everyone occasionally experiences sleeplessness, chronic insomnia is an ongoing, often debilitating condition. After a night of too little sleep, those with insomnia report impaired mental and physical abilities, diminished memory, reduced alertness, and impaired reaction time.
And although sleep disorders can be debilitating in and of themselves--over time they can spur additional health problems by weakening your immune system and decreasing your natural resistance to infection, depression, cell breakdown, and disease.
How much sleep is enough varies. Although 7 1/2 hours of sleep is about average, some people do fine on 4 or 5 hours of sleep. Other people need 9 or 10 hours a night.Daytime irritability
Common Causes of Insomnia To Rule Out
Anxiety: Everyday anxieties may keep your mind too alert to fall asleep.
Depression: due to chemical imbalances in your brain or because worries that accompany depression may keep you from relaxing enough to fall asleep when you want to.
Stimulants. Prescription drugs, including some antidepressant, high blood pressure and steroid medications, can interfere with sleep. Many over-the-counter (OTC) medications, including some pain medication combinations, decongestants and weight-loss products, contain caffeine and other stimulants.
Change in your environment or work schedule.Travel or working a late or early shift can disrupt your body's normal sleep rhythms, making you unable to get to sleep when you want to.
Medical conditions that cause pain These include arthritis, fibromyalgia and neuropathies, among other conditions.
Eating too much too late in the evening. Having a light snack before bedtime is OK, but eating too much may cause you to feel physically uncomfortable while lying down, making it difficult to get to sleep. Many people also experience heartburn, a backflow of food from the stomach to the esophagus after eating. This uncomfortable feeling may keep you awake.
Clinical Lab Assessments
Some of the following laboratory testing can provide information necessary for diagnosis and treatment. In addition, the tests listed may also give insight to functional metabolism and functional nutrient status in the body.
Amino Acid Profile
The right balance of amino acids can improve the quality of sleep and decrease the time it takes to fall asleep at night.
Several amino acids have impact on healthy sleep patterns. One of these amino acids, tryptophan, has been called a "natural hypnotic" for its important role in the biochemical mechanism of sleep. Research has shown tryptophan improves the quality of sleep and reduces sleep latency--without giving rise to the negative effects on memory and cognitive performance that are often seen in association with benzodiazepine drugs.
Adrenal Function Profiles
High levels of cortisol are associated with stress, restlessness, and the inability to sleep deeply throughout the night.
The adrenal glands release cortisol as a response to stress--in effect prolonging the body's "fight or flight "response. Oversecretion or a disrupted secretion pattern of cortisol can drastically interfere with sleep patterns. Thus cortisol imbalances can result not only in insomnia, but in the tendency to wake often during the night, and to feel "unrefreshed" even after getting a full night's sleep.
Another hormone produced by the adrenals, DHEA, serves to balance some of the effects of cortisol. For example, studies show that DHEA can significantly increase REM (rapid eye movement) time during sleep.
Insulin and Cortisol:
The interactions of these hormones in the sleep-wake cycle have been found to be significant.
Melatonin is known as the body's "biological clock," for its crucial role plays a crucial role in regulating body temperature and the sleep-wake cycle.
A Comprehensive Melatonin Profile can reveal abnormal levels of melatonin that may be significantly disrupting healthy sleep patterns.
Conventional treatment of insomnia includes the use of antihistamines, sedative hypnotic drugs (benzodiazepines), antidepressants, or a combination of the above. The prescription medications most commonly used to treat insomnia include zolpidem (Ambien®), zaleplon (Sonata®), estazolam (ProSom®), flurazepam (Dalmane®), temazepam (Restoril®), and triazolam (Halcion®). Though these agents are beneficial, they often become less effective over time.
Melatonin reportedly is effective in improving sleeping patterns in phase shift workers and people who have trouble sleeping due to what is called delayed sleep phase syndrome.
Melatonin products are available as regular tablets (or capsules), sublingual tablets, and timed-release tablets. Sublingual tablets, which are fast acting, work best for people who have difficulty falling asleep. Timed-release products work better for people who wake up during the night. Some take both, a sublingual to get to sleep and a timed-released tablet to help them have a better chance of sleeping through the night.
5-HTP (5-Hydroxytryptophan) is the immediate precursor to serotonin, which is converted into melatonin in the brain. Thus, 5-HTP is a product that can be used to improve sleep patterns. Animal studies report that 5-HTP is significantly more effective than tryptophan at inducing dose-dependent changes in sleep-wake activity.
Passionflower has been reported to have sedative, hypnotic, antispasmodic, and anodyne properties. Passionflower has been reported effective when used in combination with other sedative and anti-anxiety herbs such as valerian.
Valerian has long been used as an agent to soothe the nervous system in response to stress. Valerian root makes getting to sleep easier and increases deep sleep and dreaming. It has been reported that valerian helps improve sleep quality. Valerian does not seem to produce the morning drug hangover effect as seen with some benzodiazepines.
A double-blind trial found that valerian extract(600 mg 30 minutes before bedtime for 28 days) is comparable in efficacy to oxazepam (Serax®), a commonly prescribed drug for insomnia.
--Institute fur Psychomatische Forschung, Stuttgart, Germany. 2002
Hops was reported to improve sleep disturbances when given in combination with other sedative herbs such as valerian root and passionflower.
15 Tips for Better Sleep
Try one or two of the following tips or a combination until you have enough quality sleep to feel alert and well rested. If these tips don't work, see your doctor. You could have a sleep disorder, such as obstructive sleep apnea, that requires medical attention.People who wake up during the middle of the night do so because of hypoglycemia. Consuming a small snack just before bedtime helps to stabilize blood sugar levels throughout the night. Ideally, snacks should consist of complex carbohydrates, along with a little fat and protein. This allows for more of a timed-release breakdown and release of energy into the body.
Food allergy may also contribute to insomnia. In a trial involving eight infants, chronic insomnia was traced to an allergy to cow’s milk. Avoidance of milk resulted in a normalization of sleep patterns.
Born J, et al. Night-time plasma cortisol secretion is associated with specific sleep stages. Bio Psychiat 1986;21:1415-1424.
Born J, et al. Gluco- and antimineralocorticoid effects on human sleep: a role of central corticosteroid receptors. Amer J Physiol 1991;260(2 Pt 1):E183-E188.
Dahlitz M, Alvarez B, Vignau J, English J, Arendt J, Parkes JD. Delayed sleep phase syndrome response to melatonin. Lancet 1991;337: 1121-1124.
Dollins AB, Zhdanova IV, Wurtman RJ, Lynch HJ, Deng MH. Effect of inducing nocturnal serum melatonin concentrations in daytime on sleep, mood, body temperature, and performance. Proc Natl Acad Sci USA 1994;91:1824-1828.
Petrie K, Dawson AG, Thompson L, Brook R. A double-blind trial of melatonin as a treatment for jet lag in international cabin crew. Biol Psychiatry 1993;33: 526-53.
Jan EJ, O'Donnell ME. Use of melatonin in the treatment of paediatric sleep disorders. J Pineal Res 1996;21(4):193-9.
Onen SH, Onen F, Bailly D, Parquet P. Prevention and treatment of sleep disorders through regulation of sleeping habits. Presse Med 1994;23(10):485-9.
Spinweber CL. L-tryptophan administered to chronic sleep-onset insomniacs: late-appearing reduction of sleep latency. Psychopharmacology 1986;90(2):151-5.
Schneider-Helmert D, Spinweber CL. Evaluation of L-tryptophan for treatment of insomnia: a review. Psychopharmacology 1986;89(1):1-7.
Williams DC. Periodic limb movements of sleep and the restless legs syndrome. Va Med Q 1996;123(4):260-5.
Fitten LJ, et al. L-tryptophan as a hypnotic in special patients. J Am Geriat Soc. 1985;33:294.
Van Cauter E, Blackman JD, Roland D, Spire JP, Refetoff S, Polonsky KS. Modulation of glucose regulation and insulin secretion by circadian rhythmicity and sleep. J Clin Invest. Sep1991;88(3):934-42.
Beyer CE, Steketee JD, Saphier D. Antioxidant properties of melatonin - an emerging mystery. Biochem Pharmacol. Nov1998;56(10):1265-72.
Kayumov L, et al. Melatonin, sleep, and circadian rhythm disorders. Semin Clin Neuropsychiatry. Jan2000;5(1):44-55.
Skene DJ, et al. Use of melatonin in the treatment of phase shift and sleep disorders. Adv Exp Med Biol. 1999;467:79-84.
Dagan Y, et al. Evaluating the role of melatonin in the long-term treatment of delayed sleep phase syndrome (DSPS). Chronobiol Int. Mar1998;15(2):181-90.
Imeri L, et al. 5-Hydroxytryptophan, but not L-tryptophan, alters sleep and brain temperature in rats. Neuroscience. 2000;95(2):445-52.
Soulimani R, et al. Behavioural Effects of Passiflora incarnata L. and Its Indole Alkaloid and Flavonoid Derivatives and Maltol in the Mouse. J Ethnopharmacol. Jun1997;57(1):11-20.
Bourin M, et al. A Combination of Plant Extracts in the Treatment of Outpatients with Adjustment Disorder with Anxious Mood: Controlled Study Versus Placebo. Fundam Clin Pharmacol. 1997;11(2):127-132.
Speroni E, et al.Neuropharmacological Activity of Extracts from Passiflora incarnata. Planta Med. Dec1988;54(6):488-491.
Lindahl O, Lindwall L. Double Blind Study of Valerian Preparations. Pharmacol Biochem Behav. 1989;32(4):1065-66.
Leathwood PD, et al. Aqueous Extract of Valerian Root (Valeriana officinalis L.) Improves Sleep Quality in Man. Pharmacol Biochem Behav. 1982;17:65-71.
Balderer G, et al. Effect of Valerian on Human Sleep. Psvchopharmacology. 1985;87:406-09.
Santos MS, et al. Synaptosomal GABA Release as Influenced by Valerian Root Extract--Involvement of the GABA Carrier. Arch Int Pharmacodyn Ther. 1994;327(2):220-31.
Haimov I, Laudon M, Zisapel N, et al. Sleep disorders and melatonin rhythms in elderly people. BMJ 1994;309:167.
Singer C, McArthur A, Hughes R, et al. Melatonin and sleep in the elderly. J Am Geriatr Soc 1996;44:51 [abstr #A1].
Attenburrow MEJ, Dowling BA, Sharpley AL, Cowen PJ. Case-control study of evening melatonin concentration in primary insomnia. BMJ 1996;312:1263–4.
Zhdanova IV, Wurtman RJ, Lynch HJ, et al. Sleep-inducing effects of low doses of melatonin ingested in the evening. Clin Pharmacol Ther 1995;57:552–8.
James SP, Sack DA, Rosenthal NE, Mendelson WB. Melatonin administration in insomnia. Neuropsychopharmacology 1989;3:19–23.
Tomoda A, Miike T, Iwatani N, et al. Effect of long-term melatonin administration on school-phobic children and adolescents with sleep disturbances. Curr Ther Res 1999;60:607–12.
Garfinkel D, Laudon M, Nof D, Zisapel N. Improvement of sleep quality in elderly people by controlled-release melatonin. Lancet 1995;346:541–4.
Schneider-Helmert D, Spinweber CL. Evaluation of L-tryptophan for treatment of insomnia: A review. Psychopharmacology (Berlin) 1986;89:1–7.
Lindsley JG, Hartmann EL, Mitchell W. Selectivity in response to L-tryptophan among insomniac subjects: a preliminary report. Sleep 1983;6:247–56.
Wyatt RJ, Zarcone V, Engelman K, et al. Effects of 5-hydroxytryptophan on the sleep of normal human subjects. Electroencephalogr Clin Neurophysiol 1971;30:505–9.
Puttini PS, Caruso I. Primary fibromyalgia syndrome and 5-hydroxy-L-tryptophan: a 90 day open study. J Int Med Res 1992;20:182–9.
Hornyak M, Voderholzer U, Hohagen F, et al. Magnesium therapy for periodic leg movements-related insomnia and restless legs syndrome: an open pilot study. Sleep 1998;21:501–5.
Leathwood PD, Chauffard F. Aqueous extract of valerian reduces latency to fall asleep in man. Planta Med 1985;51:144–8.
Leathwood PD, Chauffard F, Heck E, Munoz-Box R. Aqueous extract of valerian root (Valeriana officinalis L.) improves sleep quality in man. Pharmacol Biochem Behav 1982;17:65–71.
Dorn M. Valerian versus oxazepam: efficacy and tolerability in non-organic and non-psychiatric insomniacs: a randomized, double-blind, clinical, comparative study. Forsch KomplementärmedKlass Naturheilkd 2000;7:79–84 [in German].
Donath F, Quispe S, Diefenbach K, et al. Critical evaluation of the effect of valerian extract on sleep structure and sleep quality. Pharmacopsychiatry 2000;33:47–53.
Dressing H, Riemann D, Low H, et al. Insomnia: Are valerian/balm combination of equal value to benzodiazepine? Therapiewoche 1992;42:726–36 [in German].
Dressing H, Köhler S, Müller WE. Improvement of sleep quality with a high-dose valerian/lemon balm preparation: A placebo-controlled double-blind study. Psychopharmakotherapie 1996;6:32–40.
Cerny A, Schmid K. Tolerability and efficacy of valerian/lemon balm in healthy volunteers (a double-blind, placebo-controlled, multicentre study). Fitoterapia 1999;70:221–8.
Researched and Written on June 5, 2006