The Council for Responsible Nutrition (CRN) says it is encouraged by the results of a new study involving nearly 40,000 healthy women --- the longest and largest trial ever conducted on vitamin E.

The study, published in the July 6 edition of the Journal of the American Medical Association (JAMA), shows vitamin E significantly reduced the risk of death from cardiovascular disease and also confirmed that vitamin E is safe, reporting that taking 600 IU of vitamin E supplements every other day did not increase total mortality in healthy women.

Other WHS findings:

• 24% reduction in cardiovascular deaths among nearly 20,000 women taking vitamin E supplements over a 10-year period.
  

• For women 65 and over taking vitamin E supplements had an even greater positive effect: a 49% reduction in cardiovascular death and a 34% reduction in heart attack.
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  Reference
  

  Lee IM, Cook NR, Gaziano JM, Gordon D, Ridker PM, Manson JE, Hennekens CH, Buring JE.Vitamin E in the primary prevention of cardiovascular disease and cancer: the Women's Health Study: a randomized controlled trial. JAMA. 2005 Jul 6;294(1):56-65.